Screwdriver
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I've often wondered if it is best to be senile and active or physically incapacitated and with an alert mind. Given the option. Or a bit of both.
Oh, I know the answer to that one. You will want to keep your wits about you and incidentally, it is possible to improve and develop your mind long after your physical body loses that ability.
Without getting too maudlin, I have an incurable brain disease which annoys the hell out of my every waking moment. I would swap that for any body part any day of the week. Interestingly and perhaps back on topic, I had one week on the tactical nuke of brain inflammation management: 500mg per day (!) of Methylprednisolone. I can tell you, that really switched the lights on for me. Everything looked at least twice as bright!
On a positive note, I am on a course of preventative treatment and there are currently no new signs of damage/demyelination/lesions etc. Clearly it is only a matter of time but as we get older, it becomes obvious that is true for all of us. Nobody gets out alive...