For starters, I would turn off the Pulse, until you get the hang of welding......so just turn the Pulse Freq to zero.
Gas Pre flow, should be about 0.5-1 second.
Peak Current should be set to suit the thickness of material your welding..........
Downslope should be about 3-4 seconds
Gas After Flow about 3-4 seconds, but this and the above one will be slightly dependant on the Peak current you have (More post gas and longer slope for higher peak current)
I agree with Matt1978. Keep it simple to start with. Unless you're welding aluminium, set the AC/DC switch on the edge of your picture to DC. The "Clean Area Width" control (also known as AC balance on some welders) should be inactive for DC. Also, when the Pulse/smooth switch is set to smooth, the "Pulse Frequency" and "Pulse Duty" settings will be inactive. "Arc Force" hasn't been mentioned yet and sets how the welding current varies with changes in arc length. Best see what the manual says about this one. My guess is start at 100 and reduce to give a more stable arc.